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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '444bb1ca18309194479e364d050f2c3317bceabac0af0617a5488753fe26e2bc' 
  AND token = '8X99e2ynFKqMH3WU4/mrzw6SzGe8VZt67ZWL+NRBs4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}