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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4d49634ee9a7602760ed970ab6857a8dde1eaf80eb64424cdf1cf2f7f3c2149' 
  AND token = 'Vg6tF0W3fsAwNpzB0KdZ1e9K7+OtEUAP5BzSRjxcYgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}