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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20e6d9996a96f0bca4b631c6f42fae69437de55e24f7019c91dbd1797f4f4162' 
  AND token = 'oboYcm9Tv/P0hK7rfQ3IFmNMbVS2UBxprr5KMimPDVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}