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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c358537e991b83ef83ebe0f79f120abf07e889e4ddaca83d13063de9ac71601' 
  AND token = 'EJouuX+uzk6PteFlru9ms0LZtFrHwqkTeeR1qeUuvm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}