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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d19a50c9e814d9c50de37c68c3b1377d776419201212aa4cc5ffedac509d28c' 
  AND token = 'pWDLiEAnOPCAhbWQJBnff/qTh7R2M5O2Ibbuvjnnlv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}