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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41eda7c259d5a0a0f9162c044d2f6d610c2379a0854f71cee3427249f2f9b989' 
  AND token = 'Gu/WJ/fm3HL+ltpRmXZlhqaEej92wl6cxN7vl1yj4Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}