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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3ff6aafe5a8d6773bb7e2e7e08d21f9df38306bdf0aa3211be7704a7e12adef' 
  AND token = 'Wcwisw/PfW/tkAB3HF8sXO3cNb3kVyp9wL2Gn5y2HWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}