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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc2104224da875fa5a953fdef41bdbb5facd78b6e32800a3f9cc4932d99b8380' 
  AND token = 'dYvTZ2Emf9yV8K7v+kbLibC+JfNIZ7PVwxeEhw3iMzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}