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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8886deb90591e6b4d198103e6dde7f5397005d207715567f8f94f652fb77171' 
  AND token = 'MU7u2LCU5pmjWHM62k+For/kTlRd260ZIveY6nRa94Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}