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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d33d3285424f45cba6b054a95c29de4c7129d0b2241af245f3d4cdb9ddfd0a4' 
  AND token = 'iOeXznynAygsAqeMLv7/7o/yRG96BQl9YZwac/lTnB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}