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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae3bb33a62e53c6e2444042b7a5736ccf6e5a09c7f35a9b2820e401902bc0f6e' 
  AND token = 'XcVeB0u3t0QXSXMEZMgsfg0IHjsg1R/bx4LvMx2Tcvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}