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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45409685d3adcb92d4b1b90caa79b6d49f6ba5b5202446d9bfc7edf688bf8c1' 
  AND token = 'YZYWKfUgEn6Rs2MI7S69TSZJhCUqeohHtcsdmfp9MXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}