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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74ca3907e02ca4bf8078d72998fb55161401e0758b98291c333b431a33b7ae27' 
  AND token = 'nx/ysZBlDEgIAyaWs6Nl6kem/4nH8x6WIzG3H0FrL/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}