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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653cf9e01c33addba80e4528a6d226d5b8b4a4fee71e1ad1eb855179a0cd81b2' 
  AND token = 'VPvk4sz5c3Y/NRc18t9t8UGEvixGryQSkMJquzBN6ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}