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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c47af3a5bc15f980ff4c184018af3ea7ba90a9b3da833c2cde4f66da77f4a6' 
  AND token = 'EmDk26euTQMtCj/zaf17ruCUaW36/B6NGNrQoeFKJPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}