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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0102e5db6a9048951d4769d4afb65583a1ceab2cd1ffcb3e6428173498653602' 
  AND token = 'BhtCEEyc5RVD+9+OM4T9QaHEqFFjoJKzb13yjMGHGyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}