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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a74c37b1a539467c83a17beb194e8a9215da9ac640cd45e205905451c66ec40' 
  AND token = 'rpiD+MZ8B1GNm9U9RZk01CxLKmt+U4A1072uqaf8540=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}