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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed2b169566168a82e7222af77638cdc7686d7bfd53a0f4e0ff13e1643e4b41f' 
  AND token = 'agXzvbwCerFzuu2CRXn/4XglqoCYsQ39iYuXmLza/00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}