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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1ffb38d264fd5525aebdd28d4ab5a61e435f85bca381740698c222e95f2222f' 
  AND token = 'fgTUO32+h1AOeziVLF3em6aYVL/kg5nt1ooXsa/mNu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}