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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da10dcf72d696e38b19285468f77370c3159d088e73741eee4dfdcd82abf8a42' 
  AND token = 't87InGP/GSaFx/sVnDfpLDyeJDJFxjYPU+pVpss0E2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}