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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0e9f192a2ce740610e527c9ca3582c9bf0fefd3f20e18e75f7c344deb13753' 
  AND token = 'A/2tGmM5HfcmuSYqmYWgY8JxtRF8thGo1Pq/CNOsvIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}