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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d146ca08ac2450a8e4155e2605df2aaf3008758c9c24a1311145d89bce2639' 
  AND token = '93MUiL+LOvofDBgLt/g0Rc6dN0LbcyEO5V9CgVIdEJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}