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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1410fc8d8dbc2405ac8bb4e3a9aaa2d69e741e7d6fe71cadd914aa1adb0c37f' 
  AND token = 'VgcUIHfu8oOByNQyei7VaJPZKEhZsiRV5lHPn19BycY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}