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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b322f9ae9c47514d7d7cfbcde97a45e017ce2515c54e43e349e9695405db6d95' 
  AND token = 'uVs+GtIOKgP394LLWIwG/Vzi4Hn4/1kFPx/NFNC6YSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}