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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1371891861aaa4eaf6440ac4f297eae7e185ea338839fc4750f72fe5b5b3889' 
  AND token = 'u6H1TK3gV8BOQhLKChoCvQIwsrPW/mSBy/qhq3T9aTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}