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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be46e7e3248aa72d1d25e5b5de347cd9f8ddbf6e9b60e95b48a9a1905b69e5a4' 
  AND token = 'uoMOSoC+g5gHw2QL7s7QziUPVuepvBm70uaweYX0SH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}