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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4abd7611279ea680d15c19bde31aa65c90fd36c35e4e07c4c5e91286bbe52dd5' 
  AND token = 'CK+OOVpIyIQ7P6l2sq1fz1el3TJL9vq65X/8UDwQalk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}