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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a3cd4f13146a8f2b0e02cbf5e5bb21e27132daae66981c22d5d9010a8dcb71' 
  AND token = 'oSzgGxVjRQMEdYhhO3iv9El5P/+6Rp7dPFFycdN5Phk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}