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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f246dcbd7dc2a4d312a403bc1b2cb867723d246195af5ce879234e56c61bdfca' 
  AND token = '+HPSofzSGIUfz7yT26XO9NPyDuTnjTL/08qQmXiQ9XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}