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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49bd22e24849d5f766487c2f75a0ceaf4393d5a995d42a60b37a32ba0e80e852' 
  AND token = 'bBCkEHQBEgfuVee507EQDl6c9tZ2RdnPaL2m+XI3/ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}