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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fc7efa20764f040896434f8fddc9ce9d652a7f8ba5b0e861fc4c7855dbf8383' 
  AND token = 'z18WVCSdbTmTZBrvQ9DTd2A/I2yFwfBwR5Kp12469Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}