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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f1ba5ce1b51834a89fabef1b2cb636de8c44cd01e8f146e4723738f9b013893' 
  AND token = 'XBQYeX8tL/YfFYzMTGs+1F8Aoe1hx6hY4ExGU+EKuAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}