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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6f714d9fef97e9b9dcf0c4d56fbe3c49b69def18bed6c08c39c506565cbe30a' 
  AND token = '3OPAPjCdDN6mqQRDupt2I96I2lFAFnCP2gZFfVmmmCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}