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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4435f7e7c2144bbb87914ea716b33b97140439c7152d6542d1b829965c75bed5' 
  AND token = 'TBawwFbyifdHPMsIptCuZ+3B7cJCiQTWXegcthG3Jcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}