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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9776251c4f7dcc9dd7ee6ef5a4cab00e066bf2a4be92d06f8795b014728c2015' 
  AND token = 'gO7hSame+z2aupTn+Fli/d9Z+ZEnqi/RLRax0LzLZ4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}