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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2e927e71ff4a42c7867f2c61c81a8305ccf886a53e700282583b9b328d0d44c' 
  AND token = 'tbprsK0bZHhWVcEHTmW5UcIl+PYTN9dC8MC7nPDZ7d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}