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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d96d5cd405f62051c671c6025a8affc4ad67551d8caa9c9ad6285bcf7699c0' 
  AND token = 'khVwf+r9Seh13FfmLteKZziAsqWk6khxQtsQdm8JhBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}