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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2f8835e19d597ec219572350ec940b99abfab4b9ae40f1e059ce9fb1cc3ccd1' 
  AND token = 'YDi+OEKNs0nYJYud45wTst4pt3l7TsAUdhSgNc8ekFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}