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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd75c5fe87e7a537e53c1863c01fcde36c8a999b0820df0c28b5b17d77533e6fe' 
  AND token = 'JGpFX9eHq8x+iRZQ/6Xn5MzRVOufcRfOJ6ag6MjCps4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}