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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c31ae0a6e3dbb66c2e609bb5b939cec8b0b6afa2c782d96d0147917e151242' 
  AND token = 'xrIju5ph8NYEVMGmKcEO4CXhp57CgX/Tmpe5/R0Wl7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}