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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291604fc3e3a1060d62cac5cd1d061449e1f6760e4b61a569dbd7f09f0398751' 
  AND token = 'tr+d5JtRrPziqHUhuM6xcUq5hCM2A4x1b8brFzzkvrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}