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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f99f3bff5d45756e589a5c02663db7682c5ff8c13531c067665d70e854cd228' 
  AND token = '3tf3tYz4UobCA7jUO0SLESfMMibf3+Ls6d5W54AXZHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}