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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c5c056331ab5da80edb030dc81d006c67d3324a93d2f29fc13d2b5a5f770e04' 
  AND token = '9audbh3F7lp7XyAAaatEU9LYy8Cs2ngOW8UFGpC3Q80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}