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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2989c890ec4fec6264b55c6e8b142cd40a94c2ef9b689bbcab1950a971e7c746' 
  AND token = 'NkMEKYCewXOw/GRmuwQ4GmrSNUSoSKwSuyE5NqasWqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}