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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '464dc80569e25fc7803e1ac30f43375cdf51f170a2d76aefa6fc3c742f3e6aac' 
  AND token = 'ilrG+2kAkUETK/GqHZFK5ylrKSF01MaGqsHyAfl+m8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}