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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b656b025b4a9ab23c93fda874d2c50c32f6f2de79d2422840c275fb0fa5c561d' 
  AND token = 'vA50Avt8zxCsEpUXcwamQDO/sI9OMC6CQ3psRWk2TXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}