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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3008aec2173cc2e573caeb648341e61bd0a1865eed39497ca7f1d0ea1c798f1e' 
  AND token = 'ANfLHXL+1u8e//IpHmwx0a64a+OdW3Tz0hkeYeLcDk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}