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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ba0f2e794bf6209eed382451a9f29b7776b340e89d36ff11f6897d380df0e3' 
  AND token = 'nnfSjSu1B7piexPu7ql7zLAS1xR1IC53niQJakyW7uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}