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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216b2a0bdb84852f38b2c7716104f0d48a427f7c77b7c9a07edeb6f38dab284f' 
  AND token = 'uUelbX+A4jyElAcZ7DwA8D5aXg3IEo9llzf+VgfQJr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}