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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61ddab2515dc4d8ff69280bdf80403ac2946db77955e49cc9e88b89fd85bb152' 
  AND token = 'KKk/Pv0gA5TNTzUd83jwjcwNsUj5R0Cgb9AXKhcTo2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}